Lymphoma is the most common cancer in cats, and gastrointestinal lymphoma is the most prevalent form. Unlike in dogs, feline GI lymphoma has two dramatically different subtypes — small-cell (low-grade) and large-cell (high-grade) — with completely different prognoses and treatments. Critically, small-cell lymphoma is frequently misdiagnosed as inflammatory bowel disease (IBD), leading to incorrect treatment.
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GI lymphoma subtypes (large-cell vs small-cell) have dramatically different prognoses and treatment approaches; misclassification as IBD is common. Small-cell lymphoma and IBD can look virtually identical on ultrasound and even on biopsy if the pathologist is not experienced with feline GI disease. The distinction requires careful immunohistochemistry — and getting it wrong means treating a treatable cancer as inflammatory disease.
Accurate immunophenotyping, correct protocol selection (COP vs chlorambucil/pred), and nutritional support guidance. An oncologist confirms the diagnosis via PARR testing or immunohistochemistry, distinguishes IBD from small-cell lymphoma, and selects the appropriate chemotherapy protocol — decisions that meaningfully affect both response rate and quality of life.
Feline Lymphoma can be difficult to diagnose correctly. A specialist second opinion confirms, or revises, your pet's diagnosis before treatment begins.
Treatment choices for feline lymphoma have significant cost and outcome differences. A specialist review ensures your pet gets the most appropriate protocol.
Knowing a board-certified specialist has reviewed your pet's case gives you the confidence to make treatment decisions without second-guessing.
Every opinion is written by a board-certified oncology specialist, not a general vet. You get a detailed written report to share with your own vet, and if it does not address your case you can request a refund within 48 hours.
Board-certified specialists. Written report in 24-48 hours. 48-hour refund window.
A board-certified oncology specialist reviews your pet's complete case and delivers a written second opinion in 24-48 hours.
Submit Your Case — from $99Request a refund within 48 hours if the opinion doesn't address your case